Drugs & Vitamins

Orapred Active Ingredients: Prednisolone Liquid Representative Names: Orapred, Pediapred, Prelone Available Product Images: What are prednisolone oral solution or syrup? What should I tell my health care provider before I take this medicine? How should I take this medicine? What if I miss a dose? What drug(s) may interact with prednisolone? What side effects may I notice from taking prednisolone? What should I watch for while taking prednisolone? Where can I keep my medicine? What are prednisolone oral solution or syrup? (Back to top) PREDNISOLONE (OraPred®, Pediapred®, Prelone®) is a corticosteroid. It helps to reduce swelling, redness, itching, and allergic reactions and can be used to treat severe allergies, skin problems, asthma, arthritis and other conditions. Generic prednisolone oral solution and syrup are available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •cataracts or glaucoma •Cushing's syndrome •diabetes •heart problems, or previous heart attack •high blood pressure or blood clotting disorder •infection, such as herpes, measles, tuberculosis or chickenpox •myasthenia gravis •psychosis •osteoporosis •recent surgery •seizures (convulsions) •stomach or intestinal disease, including colitis •under-active thyroid •an unusual or allergic reaction to prednisolone, other corticosteroids, medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I take this medicine? (Back to top) Take prednisolone oral solution or syrup by mouth. Follow the directions on the prescription label. Shake well before using. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one; household spoons are not always accurate. Take with food or milk to avoid stomach upset. If you are only taking prednisolone once a day, take it in the morning, which is the time your body normally secretes cortisol. Take your doses at regular intervals. Do not take your medicine more often than directed. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) If you miss a dose, take it a soon as you can. If it is almost time for your next dose, consult your prescriber or health care professional. You may need to miss a dose or take a double dose, depending on your condition and treatment. Do not take double or extra doses without advice. What drug(s) may interact with prednisolone? (Back to top) •acetazolamide •amphotericin B •antiinflammatory drugs (NSAIDs, such as ibuprofen) •barbiturate medicines for inducing sleep or treating seizures •blood thinners •bosentan •certain heart medicines •female hormones, including contraceptives or birth control pills •live virus vaccines, and other toxoids and vaccines •medicines for diabetes •phenytoin •rifabutin •rifampin •water pills Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from taking prednisolone? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •bloody or black, tarry stools •confusion, excitement, restlessness, a false sense of well-being •eye pain, decreased or blurred vision, or bulging eyes •fever, sore throat, sneezing, cough, or other signs of infection, wounds that will not heal •frequent passing of urine •increased thirst •irregular heartbeat •menstrual problems •mental depression, mood swings, mistaken feelings of self-importance or of being mistreated •muscle cramps or weakness •nausea, vomiting •pain in hips, back, ribs, arms, shoulders, or legs •rounding out of face •skin problems, acne, thin and shiny skin •stomach pain •swelling of feet or lower legs •unusual bruising, pinpoint red spots on the skin •unusual tiredness or weakness •weight gain or weight loss Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •diarrhea or constipation •headache •increased or decreased appetite •increased sweating •nervousness, restlessness, or difficulty sleeping •upset stomach •unusual increased growth of hair on the face or body What should I watch for while taking prednisolone? (Back to top) Visit your prescriber or health care professional for regular checks on your progress. If you are taking prednisolone over a prolonged period, carry an identification card with your name and address, the type and dose of your medicine, and your prescriber's name and address. Do not suddenly stop taking prednisolone. You may need to gradually reduce the dose, so that your body can adjust. Follow the advice of your prescriber or health care professional. If you are taking prednisolone regularly, avoid contact with people who have an infection. You will have an increased risk from infection while taking prednisolone. Do not receive any vaccinations as you may get a strong reaction, and avoid people who have recently taken oral polio vaccine. Tell your prescriber or health care professional if you are exposed to anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly. If you are going to have surgery, tell your prescriber or health care professional that you have received prednisolone within the last twelve months. If you receive prednisolone every day, you may need to watch your diet. Your body can lose potassium while you are taking this medicine. Ask your prescriber or health care professional about your diet. Prednisolone can affect your blood sugar. If you are diabetic check with your prescriber or health care professional if you need help adjusting the dose of your diabetic medicine. Alcohol can increase the risk of getting serious side effects while you are taking prednisolone. Avoid alcoholic drinks. Prednisolone can interfere with certain lab tests and can cause false skin test results. People who are taking certain dosages of prednisolone may need to avoid immunization with certain vaccines or may need to have changes in their vaccination schedules to ensure adequate protection from certain diseases. Make sure to tell your prescriber or health care professional that you are taking prednisolone before receiving any vaccine. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Prelone® and PediaPred® may be stored at controlled room temperature. Orapred® must be stored in the refrigerator at 2—8 degrees C (36—46 degrees F). Do not freeze. Throw away any unused medicine after the expiration date. Last Updated:02/10/2002 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.